Prof. Dr.-Ing. Alexander Grünberger

Dr. Nadja Alina Henke

Recent Publications


Decoding bioprocesses with transcriptomics: current status and future potential
Henke, N. A.; Pucker, B.; Grünberger, A.
2026. Biotechnology Advances, 86, 108736. doi:10.1016/j.biotechadv.2025.108736
Production of Ultraviolet A protectant C50 carotenoid decaprenoxanthin by metabolically engineered Corynebacterium glutamicum
Stegelmann, F.; Seeger, J.; Peters-Wendisch, P.; Henke, N. A.; Wendisch, V. F.
2026. Bioresource Technology, 439, 133319. doi:10.1016/j.biortech.2025.133319
Flow fermentation: microsystems for whole-cell bioproduction processes
Hollmann, L.; Blank, L. M.; Grünberger, A.
2025. Trends in Biotechnology, 43 (7), 1528–1539. doi:10.1016/j.tibtech.2024.12.007
Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges
Espinoza Miranda, S. S.; Abbaszade, G.; Hess, W. R.; Drescher, K.; Saliba, A.-E.; Zaburdaev, V.; Chai, L.; Dreisewerd, K.; Grünberger, A.; Westendorf, C.; Müller, S.; Mascher, T.
2025. Microbiology and Molecular Biology Reviews, 89 (1). doi:10.1128/mmbr.00138-24
Tracking One-in-a-Million: Large-Scale Benchmark for Microbial Single-Cell Tracking with Experiment-Aware Robustness Metrics
Seiffarth, J.; Blöbaum, L.; Paul, R. D.; Friederich, N.; Sitcheu, A. J. Y.; Mikut, R.; Scharr, H.; Grünberger, A.; Nöh, K.
2025. Computer Vision – ECCV 2024 Workshops – Milan, Italy, September 29–October 4, 2024, Proceedings, Part XVI. Ed.: A. Del Bue, 318 – 334, Springer Nature Switzerland. doi:10.1007/978-3-031-91721-9_20
Supercritical carbon dioxide extraction of astaxanthin from Corynebacterium glutamicum
Seeger, J.; Zäh, M.; Wendisch, V. F.; Brandenbusch, C.; Henke, N. A.
2025. Bioresources and Bioprocessing, 12 (1), Article no: 46. doi:10.1186/s40643-025-00882-9
Producing food from CO2 using microorganisms: Lots to do, little to lose!
Minden, S.; Grünberger, A.; van der Schaaf, U.; Neumann, A.; Rösch, C.; Sauer, J.; Kaster, A.-K.
2024. Trends in Food Science & Technology, 154, Article no: 104778. doi:10.1016/j.tifs.2024.104778
Customizable and Interactive Visualizations for Investigating Spatio-Temporal Single-Cell Information
Seiffarth, J.; Blöbaum, L.; Grünberger, A.; Nöh, K.
2024. 2024 IEEE International Symposium on Biomedical Imaging (ISBI), Athen, 27th-30th May 2024, 1–5, Institute of Electrical and Electronics Engineers (IEEE). doi:10.1109/ISBI56570.2024.10635297
Enset Biomass: A promising Feedstock for Biorefinery Valorisation. PhD dissertation
Seid, N. A.
2024, July 25. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000172749
Towards Small Scale: Overview and Applications of Microfluidics in Biotechnology
Enders, A.; Grünberger, A.; Bahnemann, J.
2024. Molecular Biotechnology, 66 (3), 365–377. doi:10.1007/s12033-022-00626-6
Time-resolved cell-to-cell heterogeneity of Listeria innocua after nisin exposure
Fante, N.; Desiderato, C. K.; Riedel, C. U.; Grünberger, A.
2024. Frontiers in Bioengineering and Biotechnology, 12, Art.-Nr.: 1408652. doi:10.3389/fbioe.2024.1408652
High-throughput detection of potential bacteriocin producers in a large strain library using live fluorescent biosensors
Otto, S. J.; Teichmann, L.; Fante, N.; Crauwels, P.; Grünberger, A.; Neddermann, T.; Riedel, C. U.
2024. Frontiers in Bioengineering and Biotechnology, 12, Art.-Nr.: 1405202. doi:10.3389/fbioe.2024.1405202
Enhancing astaxanthin biosynthesis and pathway expansion towards glycosylated C40 carotenoids by Corynebacterium glutamicum
Göttl, V. L.; Meyer, F.; Schmitt, I.; Persicke, M.; Peters-Wendisch, P.; Wendisch, V. F.; Henke, N. A.
2024. Scientific Reports, 14 (1), Art.-Nr.: 8081. doi:10.1038/s41598-024-58700-9
Quantifying microbial robustness in dynamic environments using microfluidic single-cell cultivation
Blöbaum, L.; Torello Pianale, L.; Olsson, L.; Grünberger, A.
2024. Microbial Cell Factories, 23 (1), Art.-Nr.: 44. doi:10.1186/s12934-024-02318-z
Protocol to perform dynamic microfluidic single-cell cultivation of C. glutamicum
Blöbaum, L.; Täuber, S.; Grünberger, A.
2023. STAR Protocols, 4 (3), Art.-Nr.: 102436. doi:10.1016/j.xpro.2023.102436
Estimating environmental impacts of early-stage bioprocesses
Wowra, K.; Hegel, E.; Scharf, A.; Grünberger, A.; Rosenthal, K.
2023. Trends in Biotechnology, 41 (9), 1199–1212. doi:10.1016/j.tibtech.2023.03.011
Microfluidic single-cell scale-down systems: introduction, application, and future challenges
Täuber, S.; Grünberger, A.
2023. Current Opinion in Biotechnology, 81, Art.-Nr.: 102915. doi:10.1016/j.copbio.2023.102915
Experimental estimation: A comparison of methods for Corynebacterium glutamicum from lab to microfluidic scale
Steinhoff, H.; Finger, M.; Osthege, M.; Golze, C.; Schito, S.; Noack, S.; Büchs, J.; Grünberger, A.
2023. Biotechnology and Bioengineering, 120 (5), 1288–1302. doi:10.1002/bit.28345
Reliable cell retention of mammalian suspension cells in microfluidic cultivation chambers
Schmitz, J.; Stute, B.; Täuber, S.; Kohlheyer, D.; Lieres, E. von; Grünberger, A.
2023. Scientific reports, 13 (1), Art.-Nr.: 3857. doi:10.1038/s41598-023-30297-5
Fitness cost associated with cell phenotypic switching drives population diversification dynamics and controllability
Henrion, L.; Martinez, J. A.; Vandenbroucke, V.; Delvenne, M.; Telek, S.; Zicler, A.; Grünberger, A.; Delvigne, F.
2023. Nature Communications, 14 (1), Art.-Nr.: 6128. doi:10.1038/s41467-023-41917-z
Microbial lifelines in bioprocesses: From concept to application
Blöbaum, L.; Haringa, C.; Grünberger, A.
2023. Biotechnology Advances, 62, Art.-Nr.: 108071. doi:10.1016/j.biotechadv.2022.108071
Data for - Tracking one in a million: Performance of automated tracking on a large-scale microbial data set (1.0.0) [Data set]
Seiffarth, J.; Blöbaum, L.; Löffler, K.; Scherr, T.; Grünberger, A.; Scharr, H.; Mikut R.; Nöh, K.
2022, October 28. doi:10.5281/zenodo.7260137
Data for - Tracking one-in-a-million: Large-scale benchmark for microbial single-cell tracking with experiment-aware robustness metrics
Seiffarth, J.; Blöbaum, L.; Löffler, K.; Scherr, T.; Grünberger, A.; Scharr, H.; Mikut, R.; Nöh, K.
2022. doi:10.5281/zenodo.7260136
Machine learning in bioprocess development: From promise to practice
Helleckes, L. M.; Hemmerich, J.; Wiechert, W.; von Lieres, E.; Grünberger, A.
2022. doi:10.48550/arXiv.2210.02200
Machine learning in bioprocess development: from promise to practice
Helleckes, L. M.; Hemmerich, J.; Wiechert, W.; von Lieres, E.; Grünberger, A.
2022. Trends in Biotechnology, 41 (6), 739–752. doi:10.1016/j.tibtech.2022.10.010