New Publication on Transcriptomics in Bioprocess Engineering
Nadja Henke and Alexander Grünberger have published a new paper on the use of transcriptomics to decode and optimize bioprocesses. The review summarizes the current state of RNA-Seq–based approaches and highlights their value for strain characterization, process optimization, and understanding cellular responses under industrial conditions. This study resulted from a great collaboration with Boas Pucker (University of Bonn).
Read more here.
New Article has been Published
We are happy that a new article from our research group was published by Yannick Scholz, Boris Yermakov and Alexander Grünberger in Current Opinion in Biotechnology. The paper introduces the concept of Microfluidic Windows of Operation (MWOs), adapting an established framework from bioprocess engineering to microfluidic single-cell cultivation systems. The proposed approach supports early-stage experimental design by systematically linking operating parameters with biological and technical constraints. By making key parameter interdependencies visible, MWOs aim to improve experimental robustness, enable more rational system design, and enhance comparability between microfluidic platforms.
The work contributes to advancing robust microfluidic experimentation and provides practical guidance for both new and experienced users of microfluidic single-cell cultivation systems. Read more: open access
Christmas Party 2025
To wrap up the year, we went bowling together and enjoyed a meal as a team. Before that, we made sure our labs were thoroughly cleaned and ready for a fresh start. We wish everyone a wonderful Christmas and relaxing holidays. We’re already looking forward to the exciting projects awaiting us in the coming year.
Group Retreat in Annweiler am Trifels
Last month, our research group spent a few days in the mountains of Annweiler am Trifels for our first retreat. Being away from the lab created time to talk about ongoing projects and share thoughts. Alongside the presentations and discussions, we enjoyed a hike through the autumn landscape and some good food. The quiet surroundings made it easy to step back and look at our work from a different angle. We’re already looking forward to next year.
Faculty Teaching Award 2025 for Alexander Grünberger
Alexander Grünberger received the KIT Faculty Teaching Award in 2025. Together with Ulrike van der Schaaf, Dirk Holtmann, and Jürgen Hubbuch, he was honored for the redesigned lecture “Introduction to Bioengineering” at the Faculty of Chemical and Process Engineering. The team fundamentally restructured the course, closely linking theoretical foundations with practical, application-oriented examples. This approach provides students with a hands-on introduction to key topics in bioengineering and helps spark early enthusiasm for the field. Find more: KIT Faculty Teaching Award 2025
